Product Name :
PRSS2 Rabbit Polyclonal Antibody
Predicted band size :
Observed band size :
Synonyms:
Anionic trypsinogen antibody EC 3.4.21.4 antibody MGC111183 antibody MGC120174 antibody Protease serine 2 preproprotein antibody Protease, serine, 2 (trypsin 2) antibody Protease, serine, 2 antibody Protease, serine, 2, preproprotein antibody Prss2 antibody Serine protease 2 antibody 展开
Function :
This gene belongs to the trypsin family of serine proteases and encodes anionic trypsinogen. It is part of a cluster of trypsinogen genes that are located within the T cell receptor beta locus. Enzymes of this family cleave peptide bonds that follow lysine or arginine residues. This protein is found at high levels in pancreatic juice and its upregulation is a characteristic feature of pancreatitis. This protein has also been found to activate pro-urokinase in ovarian tumors, suggesting a function in tumor invasion. In addition, this enzyme is able to cleave across the type II collagen triple helix in rheumatoid arthritis synovitis tissue, potentially participating in the degradation of type II collagen-rich cartilage matrix. Alternative splicing results in multiple transcript variants.
Antibody Type:
Rabbit Polyclonal Antibody
Immunogen :
Recombinant protein within human PRSS2 aa 1-120.
Species reactivity:
Human, Rat, Mouse
Verify application:
WB, IHC-P, IF-Cell
Coupling :
unconjugated
Clone number:
RRID:
AB_3071279
Form :
Liquid
Concentration :
1ug/ul
Storage instructions:
Store at +4℃ after thawing.5-Bromo-3-chlorobenzo[d]isoxazole Data Sheet Aliquot store at -20℃.2454490-66-3 Price Avoid repeated freeze / thaw cycles.PMID:33738906
Storage buffer solution:
1*TBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Subtype:
IgG
Purification method :
Immunogen affinity purified.
ELTSA :
Molecular weight :
26 kDa
Positive control :
Human small intestine tissue lysates, rat pancreas tissue, human pancreas tissue, mouse pancreas tissue, SH-SY5Y.