Product Name :
2-Methylthioadenosine Triphosphate Sodium Salt (CAS 100020-57-3)
Synonym :
2-(methylthio)-adenosine-s′-(tetrahydrogen triphosphate) sodium salt
Application :
2-Methylthioadenosine Triphosphate Sodium Salt is an ATP analogue which acts as a P2Y agonist
CAS:
100020-57-3
Purity:
Molecular Weight:
641.20
Formula :
C11H14N5O13P3S•4Na
Physical state:
Solid
solubility :
Soluble in water (13 mg/ml).
Shipping Condition :
Store at -80° C
Melting point:
SMILES:
CSC1=NC2=C(C(=N1)N)N=CN2[C@H]3[C@@H]([C@@H]([C@H](O3)COP(=O)([O-])OP(=O)([O-])OP(=O)([O-])[O-])O)O.[Na+]
References:
:Cyclic GMP-dependent relaxation of isolated rat renal glomeruli induced by extracellular ATP. | Jankowski, M., et al. 2001. J Physiol. 530: 123-30. PMID: 11136864P2y1 and P2y2 receptor-operated Ca2+ signals in primary cultures of cardiac microvascular endothelial cells. | Moccia, F., et al. 2001. Microvasc Res. 61: 240-52. PMID: 11336535Effects of purinoceptor agonists on electrophysiological properties of rat mesencephalic trigeminal neurones in vitro. | Regenold, JT., et al. 1988. Neurosci Lett. 92: 347-50. PMID: 3200490Studies on the stereoselectivity of the P2-purinoceptor. | Burnstock, G., et al. 1983. Br J Pharmacol. 79: 907-13. PMID: 6317121Specific but noncompetitive inhibition by 2-alkylthio analogues of adenosine 5′-monophosphate and adenosine 5′-triphosphate of human platelet aggregation induced by adenosine 5′-diphosphate.2306261-01-6 supplier | Cusack, NJ.3-(3-Butyn-1-yl)-3H-diazirine-3-ethanol Data Sheet and Hourani, SM.PMID:33559526 1982. Br J Pharmacol. 75: 397-400. PMID: 7186826Expression of a cloned P2Y purinergic receptor that couples to phospholipase C. | Filtz, TM., et al. 1994. Mol Pharmacol. 46: 8-14. PMID: 8058061Differential heterologous and homologous desensitization of two receptors for ATP (P2y purinoceptors and nucleotide receptors) coexisting on endothelial cells. | Wilkinson, GF., et al. 1994. Mol Pharmacol. 45: 731-6. PMID: 8183253Heterogeneity of ATP receptors in aortic endothelial cells. Involvement of P2y and P2u receptors in inositol phosphate response. | Motte, S., et al. 1993. Circ Res. 72: 504-10. PMID: 8431980Second messenger cascade specificity and pharmacological selectivity of the human P2Y1-purinoceptor. | Schachter, JB., et al. 1996. Br J Pharmacol. 118: 167-73. PMID: 8733591Identification of competitive antagonists of the P2Y1 receptor. | Boyer, JL., et al. 1996. Mol Pharmacol. 50: 1323-9. PMID: 8913364Regulation of brain capillary endothelial cells by P2Y receptors coupled to Ca2+, phospholipase C and mitogen-activated protein kinase. | Albert, JL., et al. 1997. Br J Pharmacol. 122: 935-41. PMID: 9384512Control of massive prostatic bleeding with angiographic techniques. | Mitchell, ME., et al. 1976. J Urol. 115: 692-5. PMID: 940204Competitive and selective antagonism of P2Y1 receptors by N6-methyl 2′-deoxyadenosine 3′,5′-bisphosphate. | Boyer, JL., et al. 1998. Br J Pharmacol. 124: 1-3. PMID: 9630335